Department Seminar

Upcoming Seminar

Intra and extracellular mechanisms regulating AMPA receptor trafficking and synaptic docking
Dr. Javier Diaz Alonso, UC Irvine

March 12, 2025
4:00pm-5:00pm in HSCI-105

Javier Diaz Alonso

AMPA receptors (AMPAR) are the main mediators of fast excitatory synaptic transmission throughout the brain. The Diaz Alonso lab investigates the molecular mechanisms regulating AMPAR trafficking and docking at synapses. We focus on long-term potentiation, a form of synaptic plasticity which contributes to learning and memory formation. I will discuss recent work from our lab focusing on two different areas of the receptor complex: the extracellular amino-terminal domain, and the auxiliary AMPAR regulatory proteins TARPs.

simplified model for AMPA receptor (AMPAR) accumulation at synapses
Fig.: A simplified model for AMPA receptor (AMPAR) accumulation at synapses. The stabilization of laterally diffusing AMPARs involves the concerted interactions between elements of the AMPAR complex such as the GluA1 extracellular, amino-terminal domains (ATDs) with extracellular docking sites, or "slots"; and that of the AMPAR auxiliary proteins TARPs with intracellular slots. The availability of AMPAR slots is regulated by synaptic activity, in turn regulating access of AMPAR to the synapse and ultimately gauging synaptic strength.

Seminars are held on Wednesdays at 4:00pm. All are invited to attend.

Seminar Coordinator

For information and suggestions about our Department Seminar series, please contact the seminar coordinator:

Dr. Fangyuan Tian
Fangyuan.Tian@csulb.edu

Schedule

The following schedule is for Spring 2025.

Seminar Schedule
DateTitleSpeaker and Affiliation
March 12, 2025Intra and extracellular mechanisms regulating AMPA receptor trafficking and synaptic dockingDr. Javier Diaz Alonso, UC Irvine
March 19, 2025Defining the Pathways of Eukaryotic Translational Quality ControlDr. Michael Lawson, UCLA
March 26, 2025The "Rippled" Beta-Sheet: An Old Theory by Pauling and Corey Inspires New BiomaterialsDr. Jevgenij Raskatov, UC Santa Cruz
April 9, 2025Fundamental Studies of Microporous Polymers and their Applications in BiomedicineDr. James Bour, Wayne State University
April 16, 2025Part 1: Some Studies with Chiral Compounds and Stereoselection;
Part 2: Organophosphorus Compounds as Butyrylcholinesterase Inhibitors		Dr. Ken Nakayama, CSU Long Beach
April 23, 2025TBADr. Alina Schimpf, UC San Diego
April 30, 2025TBADr. Xia Yang, UCLA
May 2, 2025Predicting Thermoelectric Performance with Artificial IntelligenceDr. Holger Kleinke, University of Waterloo
May 7, 2025Moiré excitons in van der Waals MaterialsDr. Gang Lu, CSU Northridge

Previous Seminars

Previous Spring 2025 Seminars
DateTitleSpeaker and Affiliation
March 5, 2025Chemical Approaches to Perturb and Illuminate Biological ProcessesDr. Chao Zhang, USC
February 26, 2025Chemical and Physical Properties of Independence Day Fireworks Aerosol Particle Emissions in Southern CaliforniaDr. Daniel Curtis, CSU Fullerton
February 19, 2025Single molecule investigation of liquid-liquid and liquid-solid phase separation of amyloid proteinsDr. Kanchan Garai, Tata Institute of Fundamental Research, Hyderabad, India
February 12, 2025Bio-Integrated Nanoelectronics for Precision Medicine and BiomanufacturingDr. Deependra Ban, UC San Diego
February 5, 2025Dynamically Tunable Plasmonic Surfaces using Oscillatory Electric FieldsDr. Regina Ragan, UC Irvine
January 29, 2025Beginning to understand light-mediated Ni catalysis using physical organic techniques and data scienceDr. Ana Bahamonde, UC Riverside

The Seminar Archive has Department Seminars from previous semesters.

The Department Seminar is supported by The Allergan Foundation.